Okay, here's an idea....
On these spam websites is a contact page.
You can click that and send them rude messages, but what good will that do? Waste of time.
However, I think it would be interesting to send them what might seem a legit message to (1) waste their time and (2) for a return contact phone number put the phone number of your local FBI, ATF, DEA offices and/or even local police.
So, that's what I've been doing. Make these cocksucking mail order med spam companies call the DEA offices. How hilarious is that?